Iinaliti ezingenaliti ziguqula ulawulo lwamayeza kunye nezitofu zokugonya, zinika enye indlela engenabuhlungu nesebenzayo kwiindlela zemveli ezisekelwe kwiinaliti.Olu lutsha lubaluleke kakhulu ekwandiseni ukuthotyelwa kwesigulane, ukunciphisa umngcipheko wokulimala kweenaliti, kunye nokunciphisa ixhala elinxulumene nokutofa kweenaliti.
Imiba yobuNjineli
Indlela yokwenza
Izitofu ezingenanaliti zihambisa amayeza ngejethi yolwelo enesantya esiphezulu, ethi igqobhoze eluswini ize ifake iyeza kwizicubu ezingaphantsi. Le ndlela ixhomekeke kumacandelo amathathu angundoqo:
Umthombo wamandla: Oku kunokuba yintwasahlobo, igesi ecinezelweyo, okanye i-piezoelectric element eyenza amandla ayimfuneko ukudala umjelo wejethi.
Drug Reservoir: Igumbi eligcina amayeza ukuba ahanjiswe.
Umbhobho: Ikroba elincinane apho iyeza likhutshwa ngesantya esiphezulu.
Iindidi zezitofu ezingenanaliti
I-Spring-Loaded Injectors: Ezi zisebenzisa indlela yasentwasahlobo ukuvelisa uxinzelelo olufunekayo. Xa intwasahlobo ikhutshwa, ihambisa iyeza nge-nozzle.
I-Gesi-Powered Injectors: Sebenzisa igesi ecinezelweyo, efana ne-CO2, ukwenza i-jet ye-speed-speed jet efunekayo ekuhanjisweni kweziyobisi.
I-Piezoelectric Injectors: Qasha iikristale ze-piezoelectric ezandisayo xa kusetyenziswa umsinga wombane, ukuvelisa amandla okukhupha iyeza.
Imingeni yobuNjineli ePhambili
Ukuqulunqwa kweJet: Ukuqinisekisa ukuba i-jet yomelele ngokwaneleyo ukuba ingene eluswini kodwa inganyanzelisi kangangokuba ibangele umonakalo wezicubu.
Ukuchaneka komthamo: Ulawulo oluchanekileyo kwisixa samayeza esiziswe ngenaliti nganye.
Ukuthembeka kwesixhobo: Ukusebenza okuhambelanayo kusetyenziso oluninzi ngaphandle kokusilela.
Ukukhethwa kwezinto: Ukusebenzisa izinto ezihambelana nebhayoloji kunye nezihlala ixesha elide ukuthintela ukusabela kunye nokuqinisekisa ubomi obude.Imiba yeKlinikhi
Izinto eziluncedo Phezu kwezitofu zesiNtu
Ukunciphisa iintlungu: Ukungabikho kwenaliti kunciphisa kakhulu intlungu kunye nokukhathazeka.
Ukuthotyelwa kweSigulana okuPhuculweyo: Kuluncedo kakhulu kubantwana kunye nezigulana ezithanda ukuxhathisa iinaliti.
Umngcipheko osezantsi wokwenzakala kwinaliti: Yehlisa ingozi kubasebenzi bezempilo.
Ukhuseleko olomeleziweyo: Yehlisa umngcipheko wosulelo kunye nosulelo.
Usetyenziso
Ugonyo: Luyasebenza ekunikeni amayeza okugonya, kuquka lawo omkhuhlane, imasisi, kunye ne-COVID-19.
Ukuhanjiswa kwe-insulin: Isetyenziswa ngabaguli abanesifo seswekile ukulawula i-insulin ngaphandle kwesidingo semihla ngemihla yeenaliti.
I-Anesthesia yendawo: Uqeshwe kwiinkqubo zotyando zamazinyo kunye ezincinci ukuhambisa i-anesthetics.
Unyango lweHormone yokukhula: Isetyenziselwa ukulawula iihomoni zokukhula, ngakumbi kwizigulana zabantwana.
Ukusebenza kwezonyango
Uphononongo lubonise ukuba ii-injection ezingenaliti zingakwazi ukufezekisa ukuthelekiswa, ukuba zingaphezulu, iiprofayili ze-pharmacokinetic ukuya kwiinaliti zenaliti zendabuko.Ngokomzekelo, ekuhanjisweni kwe-insulin, ezi zixhobo zibonise ukulawulwa kwe-glycemic elinganayo kunye nokwaneliseka kwesigulane esiphuculweyo.
Imingeni kunye neNgqwalasela
Iindleko: Iindleko zokuqala eziphezulu xa kuthelekiswa neesirinji eziqhelekileyo, nangona oku kunokulungiswa ngeenzuzo zexesha elide.Uqeqesho: Ababoneleli bezempilo kunye nezigulane zifuna uqeqesho olufanelekileyo lokusebenzisa izixhobo ngokufanelekileyo.
Ukuhambelana kweDivaysi: Ayiwo onke amayeza afanelekileyo ukuhanjiswa ngaphandle kwenaliti ngenxa ye-viscosity okanye ifom ye-dosage.Ukwahluka kwesikhumba: Ukwahluka kwesikhumba kunye nokuthungwa phakathi kwezigulane kunokuchaphazela ukusebenza kwenaliti.
Izalathiso zexesha elizayo
Ukuqhubela phambili kwi-microfabrication kunye nesayensi yezinto eziphathekayo kulindeleke ukuba kuphuculwe ngakumbi iteknoloji ye-injector engenanaliti.Izinto ezintsha ezifana ne-smart injectors, ezikwazi ukubeka iliso kunye nokulungelelanisa i-dosage ngexesha langempela, ku-horizon.Ukongezelela, uphando kwizicelo ezibanzi, kubandakanywa i-biologics kunye ne-gene therapies, ibambe isithembiso sokwandisa ukusetyenziswa kwezi zixhobo.
Izitofu ezingenazinaliti zimela ukutsibela phambili okubalulekileyo kubuchwepheshe bezonyango, zibonelela ngeenzuzo ezininzi kwiindlela zemveli ezisekwe kwiinaliti.Ngelixa kukho imiceli mngeni okumele yoyiswe, inkqubela phambili yeklinikhi nobunjineli kulo mmandla iyaqhubeka nokuvula indlela yeenkqubo zokuhanjiswa kweziyobisi ezisebenza kakuhle, ezikhuselekileyo, nezilungele isigulana.
Ixesha lokuposa: Jul-29-2024